On the ESXi host there is no reference to vmk50 in net-dvs indicating it has been cleanly deleted
net-dvs | grep vmk50
Environment
VMware NSX-T Data Center 2.x VMware NSX-T Data Center
Cause
nsx-opsagent running on the ESXi host creates the vmk50 hyperbus interface when the host is added to the Overlay NVDS. Due to the problem documented here, when the same ESXi host is also added to a separate VLAN NVDS this vmk50 interface is deleted in error.
Resolution
This issue is resolved in NSX-T Data Center 2.4.0
Workaround: To workaround this issue the same NVDS should be used for both Overlay and VLAN on the host.