This article provides steps against a specific issue which can affect the performance of guest operating system in your virtual machine. While the recommendations can help you with improving this performance, there might still be other factors contributing to the issue you are experiencing, which will require further troubleshooting.
Symptoms:
After upgrading to VMware ESXi 6.5.0 P01 (build 5146846) or ESXi 6.5.0d (build 5310538), you experience these symptoms:
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Windows Server 2012 R2/Windows Server 2016 virtual machines respond slowly or appear to be unresponsive.
Note: Windows 2008 R2 virtual machines are not affected.
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Applications running on the Windows Guest OS, such as an Exchange or File server run slowly.
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Virtual machine performance is degraded.